What was the main idea of Manifest Destiny?

The nation was meant to spread to the Pacific.

It was a plan to become a monarchy

It meant conquering other countries

It was about staying in one place

What was the Supreme Court's decision about Dred Scott's argument for freedom?

The Court ruled against Scott and nullified the Missouri Compromise.

The Court allowed Scott to stay in the North as a free man.

The Court decided to ignore Scott's case entirely.

The Court ruled in favor of Scott and granted him freedom.

What was one reason Southern states objected to Lincoln's election?

They felt Lincoln's anti-slavery stance threatened their way of life.

They thought he would create more jobs for them.

They believed he would lower cotton prices.

They expected him to make peace with the North.

What was the outcome of the war fought between Mexico and the United States after Texas became a state?

California remained independent

2-1 Sectional Crisis Test

2-1 The Sectional Crisis (US His Quiz)

In many cases, cells must move materials from an area of lower concentration to an area of higher concentration, or “up” their concentration gradient. Such movement of materials is known as active transport. Unlike passive transport, active transport requires a cell to expend energy. CELL MEMBRANE PUMPS Ion channels and carrier proteins not only assist in passive trans- port but also help with some types of active transport. The car- rier proteins that serve in active transport are often called cell membrane “pumps” because they move substances from lower to higher concentrations. Carrier proteins involved in facilitated diffusion and those involved in active transport are very similar. In both, the molecule first binds to a specific kind of carrier protein on one side of the cell membrane. Once it is bound to the molecule, the protein changes shape, shielding the molecule from the hydrophobic interior of the phospholipid bilayer. The protein then transports the molecule through the membrane and releases it on the other side. However, cell membrane pumps require energy. Most often the energy needed for active transport is supplied directly or indirectly by ATP. Sodium-Potassium Pump One example of active transport in animal cells involves a carrier protein known as the sodium-potassium pump. As its name sug- gests, this protein transports Na ions and K ions up their con- centration gradients. To function normally, some animal cells must have a higher concentration of Na ions outside the cell and a higher concentration of K ions inside the cell. The sodium- potassium pump maintains these concentration differences. Follow the steps in Figure 5-6 on the next page to see how the sodium-potassium pump operates. First, three Na ions bind to the carrier protein on the cytosol side of the membrane, as shown in step . At the same time, the carrier protein removes a phosphate group from a molecule of ATP. As you can see in step , the phos- phate group from the ATP molecule binds to the carrier protein. Step shows how the removal of the phosphate group from ATP supplies the energy needed to change the shape of the carrier pro- tein. With its new shape, the protein carries the three Na ions through the membrane and then forces the Na ions outside the cell where the Na concentration must remain high. 3 2 1 SECTION 2 OBJECTIVES ● Distinguish between passive transport and active transport. ● Explain how the sodium-potassium pump operates. ● Compare endocytosis and exocytosis. VOCABULARY active transport sodium-potassium pump endocytosis vesicle pinocytosis phagocytosis phagocyte exocytosis www.scilinks.org Topic: Active Transport Keyword: HM60018 mb06se_homs02.qxd 5/18/07 11:02 AM Page 103 104 CHAPTER 5 K+ K+ K+ K+ K+ K+ INSIDE OF CELL OUTSIDE OF CELL Carrier protein Cell membrane P P P P Na+ Na+ Na+ ATP ADP Na+ Na+ Na+ Na+ Na+ Na+ 1 2 3 4 5 6 At this point, the carrier protein has the shape it needs to bind two K ions outside the cell, as step shows. When the K ions bind, the phosphate group is released, as indicated in step , and the carrier protein restores its original shape. As shown in step this time, the change in shape causes the carrier protein to release the two K ions inside the cell. At this point the carrier protein is ready to begin the process again. Thus, a complete cycle of the sodium-potassium pump transports three Na ions out of the cell and two K ions into the cell. At top speed, the sodium-potassium pump can transport about 450 Na ions and 300 K ions per second. The exchange of three Na ions for two K ions creates an electrical gradient across the cell membrane. That is, the outside of the membrane becomes positively charged relative to the inside of the membrane, which becomes relatively negative. In this way, the two sides of the cell membrane are like the positive and nega- tive terminals of a battery. This difference in charge is important for the conduction of electrical impulses along nerve cells. The sodium-potassium pump is only one example of a cell membrane pump. Other pumps work in similar ways to transport important metabolic materials across cell membranes.

Astronomy Chapter 1 sections 1-2

Section 1: Numbers, Operations, and Relationships (15 marks) 1. Number Concepts (5 marks) 1.1. Decompose the following numbers into tens and ones: (2 marks) a. 34 b. 67 1.2. Count the objects in the pictures below and write the total number: (3 marks) [This section would need images of objects. You can provide images of groups of objects, e.g., 3 groups of 4 apples each and ask the students to count the total number.] 2. Solve Problems (5 marks) 2.1. Solve the following word problem using drawings: (3 marks) Samantha has 5 baskets. Each basket has 8 apples. How many apples does she have in total? Samantha has 5 × 8 = 40 5×8=40 apples. 2.2. Solve the following word problem by building up and breaking down numbers: (2 marks) There are 4 boxes. Each box has 6 chocolates. How many chocolates are there in total? There are 4 × 6 = 24 4×6=24 chocolates in total. 3. Calculations (5 marks) 3.1. Multiply the following numbers using drawings: (3 marks) a. 5 × 4 = 20 b. 4 × 5 = 20 3.2. Use a number line to solve: (2 marks) a. 3 × 5 = 15 b. 2 × 4 = 8 Section 2: Patterns, Functions, and Algebra (10 marks) 4. Number Patterns (10 marks) 4.1. Complete the number sequences: (5 marks) a. 180, 170, 160, 150, 140, 130, 120, 110, 100, 90 b. 150, 152, 154, 156, 158, 160, 162, 164, 166, 168 4.2. Count in twos and fill in the missing numbers: (5 marks) a. 102, 104, 106, 108, 110, 112, 114, 116 Section 3: Space and Shape (Geometry) (10 marks) 5. Position (10 marks) 5.1. Follow the directions to move around the classroom: (5 marks) Draw a path showing how you would move from your desk to the teacher's table by following these steps: Move 3 steps forward. Turn left and move 2 steps. Turn right and move 4 steps. [Students would draw a path based on these directions.] 5.2. Use the language of position to describe the following: (5 marks) a. The pencil is on the book. b. The chair is beside the desk. c. The bag is under the table. d. The ruler is next to the notebook. e. The eraser is inside the pencil case.

PASSIVE TRANSPORT Cell membranes help organisms maintain homeostasis by controlling what substances may enter or leave cells. Some substances can cross the cell membrane without any input of energy by the cell in a process known as passive transport. DIFFUSION The simplest type of passive transport is diffusion. Diffusion is the movement of molecules from an area of higher concentration to an area of lower concentration. This difference in the concentration of molecules across a distance is called a concentration gradient. Consider what happens when you add a sugar cube to a beaker of water. As shown in Figure 5-1, the sugar cube sinks to the bottom of the beaker. This sinking makes the concentration of sugar mole- cules greater at the bottom of the beaker than at the top. As the cube dissolves, the sugar molecules begin to diffuse slowly through the water, moving towards the lower concentration at the top. Diffusion is driven entirely by the molecules’ kinetic energy. Molecules are in constant motion because they have kinetic energy. Molecules move randomly, traveling in a straight line until they hit an object, such as another molecule. When they hit some- thing, they bounce off and move in a new direction, traveling in another straight line. If no object blocks their movement, they con- tinue on their path. Thus, molecules tend to move from areas where they are more concentrated to areas where they are less concentrated, or “down” their concentration gradient. In the absence of other influences, diffusion will eventually cause the molecules to be in equilibrium—the concentration of molecules will be the same throughout the space the molecules occupy. Returning to the example in Figure 5-1, if the beaker of water is left undisturbed, at some point the concentration of sugar molecules will be the same throughout the beaker. The sugar concentration will then be at equilibrium. SECTION 1 OBJECTIVES ● Explain how an equilibrium is established as a result of diffusion. ● Distinguish between diffusion and osmosis. ● Explain how substances cross the cell membrane through facilitated diffusion. ● Explain how ion channels assist the diffusion of ions across the cell membrane. VOCABULARY passive transport diffusion concentration gradient equilibrium osmosis hypotonic hypertonic isotonic contractile vacuole turgor pressure plasmolysis cytolysis facilitated diffusion carrier protein ion channel Sugar Water 1 2 3 FIGURE 5-1 Sugar molecules, initially in a high concentration at the bottom of a beaker, , will move about randomly through diffusion, , and eventually reach equilibrium, . At equilibrium the sugar concentration will be the same throughout the beaker. Diffusion occurs naturally because of the kinetic energy the molecules possess. 3 2 1 Copyright © by Holt, Rinehart and Winston. All rights reserved. 98 CHAPTER 5 It is important to understand that even at equilibrium the ran- dom movement of molecules continues. But because there is an equal concentration of molecules everywhere, molecules are just as likely to move in one direction as in any other. The random movements of many molecules in many directions balance one another, and equilibrium is maintained. Diffusion Across Membranes Cell membranes allow some molecules to pass through, but not others. If a molecule can pass through a cell membrane, it will diffuse from an area of higher concentration on one side of the membrane to an area of lower concentration on the other side. Diffusion across a membrane is also called simple diffusion, and only allows certain molecules to pass through the membrane. The simple diffusion of a molecule across a cell membrane depends on the size and type of molecule and on the chemical nature of the membrane. A membrane can be made, in part, of a phospho- lipid bilayer, and certain proteins can form pores in the membrane. Molecules that can dissolve in lipids may pass directly through the membrane by diffusion. For example, because of their nonpolar nature, both carbon dioxide and oxygen dissolve in lipids. Molecules that are very small but not soluble in lipids may diffuse across the membrane by moving through the pores in the membrane.

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