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Antithrombotics and such

Quiz by Yana Labinov

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21 questions
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  • Q1
    Which of the following is a reversible P2Y12 antagonist?
    Prasugrel
    Bivalirudin
    Ticagrelor
    Clopidogrel
    120s
  • Q2
    For the treatment of an acute venous thromboembolism, initial parenteral anticoagulants are not needed for therapy with:
    Dabigatran or Rivaroxaban
    A parenteral anticoagulant is always needed for at least the first week
    Rivaroxaban and apixaban
    Apixaban or Edoxaban
    120s
  • Q3
    Which of the following is a fibrin-specific thrombolytic?
    Urokinase
    Streptokinase
    Alteplase
    Funcokinase
    120s
  • Q4
    Which of the following is an oral direct thrombin inhibitor?
    Bivalirudin
    Dalteparin
    Dabigatran
    Argatroban
    120s
  • Q5
    Which of the following is a non-specific, indirect factor Xa inhibitor?
    fondaparinux
    dalteparin
    edoxaban
    warfarin
    120s
  • Q6
    Which of the following statements is true regarding UFH?
    It cannot be used in the treatment of DVT due to its unpredictable pharmacokinetics.
    It requires renal dose adjustments.
    It binds to factor Xa:IIa in a 1:1 ratio.
    It has a prolonged half-life and cab be dosed twice daily.
    120s
  • Q7
    Which of the following DOES NOT have a reversal agent?
    rivaroxaban
    heparin
    warfarin
    enoxaparin
    120s
  • Q8
    Which of the following patients would benefit from monitoring of anti-Xa levels?
    Patient on warfarin.
    67 kg patient being bridged with enoxaparin to warfarin for treatment of DVT.
    72 yo obese patient on chronic dalteparin for treatment of recurrent DVT
    85 yo patient on a heparin gtt being treated for a PE.
    120s
  • Q9
    A 72 yo male with a PMH of HTN and DM presents to the ED with chest pain. He's had this type of pain on and off for the last few days so he took an ASA 81 mg and one dose of SL NTG before coming to the ED this morninng. Labs reveal a troponin of 4.5 and he is diagnosed with NSTEMI. What is this patient's TIMI risk score?
    3
    4
    2
    5
    120s
  • Q10
    In the management of NSTEMI, the two types of treatment strategies are:
    non-invasive or ischemia directed
    Invasive or ischemia directed
    invasive or thrombolysis
    thrombolysis or ischemia directed
    120s
  • Q11
    JR is a 58 year old male who presents to the ER with chest pain concerning for ACS. Labs reveal an elevated troponin of 0.8 ng/mL. An EKG shows significant depression of the ST segment in leads V1-V6. Which of the following is the most likely diagnosis for this patient?
    NSTEMI
    non cardiac chest pain
    unstable angina
    STEMI
    120s
  • Q12
    In the absence of a contraindication, which of the following patients should receive dual antiplatelet therapy for 12 months?
    A patient with an ACS event who received a bare metal stent
    A patient with an ACS event who did not receive a stent during catheterization
    A patient with an ACS event who received a drug-eluting stent
    All of the above patients should receive dual antiplatelet therapy for 12 months (or more in some cases)
    120s
  • Q13
    Which of the following DOES NOT require binding to antithrombin III in order to exert its anticoagulant effect?
    Fondaparinux
    Bivalirudin
    Enoxaparin
    Heparin
    120s
  • Q14
    AG presents with severe chest pain, radiating to his left arm and jaw. He is extremely diaphoretic. He is diagnosed with a high risk STEMI and is started on a heparin bolus + continuous infusion. He is taken to angiography and will undergo PCI. Is it appropriate to administer a GPI?
    Yes, because he has an allergy to heparin.
    No, GPI should never be given in combination with UFH
    Yes, this is a high risk patient who's received UFH so we can use abciximab, eptifibatide or tirofiban.
    They are not indicated in STEMI
    120s
  • Q15
    Without any contraindications, which of the following medications should a patient with NSTEMI receive prior to discharge?
    ASA 325 mg and ticagrelor 80 mg po daily
    enoxaparin 1 mg/kg SC BID
    Simvastatin 40 mg and amlodipine 10
    Atorvastatin 80 mg and SL NTG
    120s

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