Bioavailability_ Pharmacology
Quiz by suraj kapoor
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- Q1
Oral formulations of a drug from different manufacturers but not having same yield of blood level
Biological inequivalent
Chemical inequivalent
None of the above
Physical inequivalent
30s - Q2
Bioavailability difference assumes practical significance in all except
Digoxin is an example
dosages needing precise control
All statements are correct
Drugs with high safety of margin
30s - Q3
Low volume of distribution of drug indicates
Drug has low half life
Drug has low efficacy
Drug is not extensively distributed to tissues
Drug has low bioavailability
30s - Q4
Mark the incorrect statement
Low volume of distribution , dialysis is easy
All are correct
Water soluble drugs have high volume of distribution
Highly plasma protein bound drug have reduced volume of distribution
30s - Q5
Main determinant of loading dose of drug
Bioavailability
Route of administration
Volume of distribution
None of the above
30s - Q6
An agent is noted to have a very low calculated volume of distribution . Which of the following is the best explanation?
Agent is sequestered in tissues
Agent is eliminated by kidneys, and the patient has renal insufficiency
Agent is extensively plasma protein bound
The agent is eliminated by zero order kinetics
30s - Q7
Which of the following has high volume of distribution?
Hydrophilic
Drug with low therapeutic index
Highly protein bound
Lipophilic
30s