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Bioavailability_ Pharmacology

Quiz by suraj kapoor

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7 questions
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  • Q1

    Oral formulations of a drug from different manufacturers but not having same yield of blood level

    Biological inequivalent

    Chemical inequivalent

    None of the above

    Physical inequivalent

    30s
  • Q2

    Bioavailability difference assumes practical significance in all except  

    Digoxin is an example

    dosages needing precise control

    All statements are correct

    Drugs with high safety of margin

    30s
  • Q3

    Low volume of distribution  of drug indicates

    Drug has low half life

    Drug has low efficacy

    Drug is not extensively  distributed to tissues

    Drug has low bioavailability

    30s
  • Q4

    Mark the incorrect statement

    Low volume of distribution , dialysis is easy

    All are correct

    Water soluble drugs  have high volume of distribution

    Highly plasma  protein bound drug have reduced volume of distribution

    30s
  • Q5

    Main determinant of loading dose of drug 

    Bioavailability

    Route of administration

    Volume of distribution

    None of the above

    30s
  • Q6

    An agent is noted to have a very low calculated  volume of distribution . Which of the following is the best explanation?

    Agent is sequestered in tissues

    Agent is eliminated  by kidneys, and the patient has renal insufficiency

    Agent is extensively plasma protein bound

    The agent is eliminated by zero order kinetics

    30s
  • Q7

    Which of the following has  high volume of distribution?

    Hydrophilic

    Drug with low therapeutic index

    Highly protein bound

    Lipophilic

    30s

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