extends outward from the ER to the plasma membrane, and inward from the plasma membrane to lysosomes,

starts with the synthesis of proteins on the ER membrane and their entry into the ER, and it leads through the Golgi apparatus to the cell surface

responsible for the ingestion and degradation of extracellular molecules, moves materials from the plasma membrane, through endosomes, to lysosomes

Major outward

Major inward

Vesicles that bud from membranes usually have a distinctive protein coat on their cytosolic surface and are therefore called __

The best-studied vesicles are those that have an outer coat made of the protein

bud from both the Golgi apparatus on the outward secretory pathway and from the plasma membrane on the inward endocytic pathway

assemble into a basketlike network on the cytosolic surface of the membrane, and it is this assembly process that starts shaping the membrane into a vesicle

A small GTP-binding protein called

assembles as a ring around the neck of each deeply invaginated coated pit.

both secure the clathrin coat to the vesicle membrane and help select cargo molecules for transport

involved in transporting molecules

The identification process depends on a diverse family of monomeric GTPases called

Specific Rab proteins on the surface of

SNAREs on the vesicle

Complementary SNAREs on the target membrane

This family of transmembrane proteins includes v-SNAREs on vesicles and t-SNAREs on target membranes

interact with complementary SNAREs on the target membrane

Molecules for onward transport carry specific transport signals that are recognized by cargo receptors

These coat proteins secure the clathrin coat to the vesicle membrane and help select cargo molecules for transport

These carry soluble proteins and membrane between compartments of the endomembrane system. They bud from one membrane and fuse with another

Newly made proteins, lipids, and carbohydrates are delivered from the ER, via the Golgi apparatus, to the cell surface by transport vesicles

Eukaryotic cells are continually taking up fluid, as well as large and small molecules, by the process of endocytosis

True or False: Transport vesicles carry soluble proteins and membrane between compartments of the endomembrane system

True or False: Adaptins secure the clathrin coat to the vesicle membrane and help select cargo molecules for transport

True or False: Cargo receptors recognize specific transport signals on molecules for onward transport

True or False: Tethering proteins capture vesicles by grabbing hold of Rab proteins

True or False: During exocytosis, the vesicle membrane becomes part of the plasma membrane

True or False: Endosomes are the destination for materials ingested by endocytosis