Ch. 4 Recap- Med Biochem
Quiz by Kari Stone
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- Q1
Which of the following statements is not true about receptors?
Receptors contain a hollow or cleft on their surface which is known as a binding site.
Receptors do not catalyse reactions on chemical messengers.
Receptors bind chemical messengers such as neurotransmitters or hormones.
Most receptors are proteins situated inside the cell.
300s - Q2
Which of the following is not a neurotransmitter?
Cyclic GMP
Glycine
γ-Aminobutyric acid
Serotonin
300s - Q3
There is a fine balance required for the binding interactions of a neurotransmitter with its receptor. Which of the following statements best expands on this statement?
It is important that the binding interactions involve a mixture of van der Waals interactions, hydrogen bonds and ionic bonds since neurotransmitters have different functional groups.
The binding interactions must be of the correct nature to match the functional groups of the neurotransmitter and the functional groups in the binding site.
There must be the correct balance of hydrophilic and hydrophobic interactions to ensure that the chemical messenger can enter a hydrophobic binding site.
The binding interactions must be of the correct nature to match the functional groups of the neurotransmitter and the functional groups in the binding site.
300s - Q4
Which of the following statements is true about a G-protein coupled receptor?
There are more extracellular loops than intracellular loops.
The binding region for the G-protein involves one of the intracellular loops and the C-terminal chain.
The N-terminal chain is intracellular and the C-terminal chain is extracellular.
It contains five transmembrane hydrophobic sections.
300s - Q5
Which of the following statements is true about a tyrosine kinase linked receptor?
It is situated in the cytoplasm.
It has one hydrophobic transmembrane region.
The ligand binding site is in the C-terminal chain.
The N-terminal chain is intracellular.
300s - Q6
Which of the following statements is true regarding intracellular receptors?
They are activated by hydrophobic molecules which are synthesised within the cell.
They consist of three protein subunits.
They contain a ligand binding site near the N-terminal end.
They contain a binding region for DNA near the middle of the protein.
300s - Q7
Which of the following reactions is catalysed by a tyrosine kinase?
The phosphorylation of an alcohol functional group.
The esterification of a phenol functional group.
The phosphorylation of a phenol functional group.
The esterification of an alcohol functional group.
300s - Q8
Which of the following terms describes the epidermal growth factor?
Bivalent ligand.
Divalent ligand.
Covalent ligand.
Heterovalent ligand.
300s