Chronic Inflammation 2024
Quiz by Sadeq K. Ali Al-Salait
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- Q1
What is the defining characteristic of chronic inflammation?
Resolution without tissue repair
Inflammation that involves multiple sites
Involvement of only neutrophils
Exclusively involves viral infections
Prolonged duration with ongoing inflammation, tissue injury, and healing
30s - Q2
Which cells are primarily involved in chronic inflammation?
Eosinophils and mast cells
Fibroblasts and keratinocytes
Macrophages, lymphocytes, and plasma cells
Neutrophils and basophils
Platelets and erythrocytes
30s - Q3
What is the central role of macrophages in chronic inflammation?
Exclusively producing antibodies
Release of histamine
Initiation of acute inflammation
Phagocytosis of microbes and dead tissues
Formation of blood clots
30s - Q4
Which of the following conditions is an example of chronic granulomatous inflammation?
Tuberculosis
Allergic rhinitis
Cholecystitis
Viral hepatitis
Asthma
30s - Q5
What is a typical cause of Langhans-type giant cells in a granuloma?
Gallstones
Non-steroidal anti-inflammatory drugs
Helicobacter pylori
Mycobacterium tuberculosis
Rheumatoid arthritis
30s - Q6
Which cytokine is crucial for the activation of macrophages during chronic inflammation?
IL-4
IFN-γ
IL-6
TNF-β
IL-10
30s - Q7
Which cell type is associated with immune reactions mediated by IgE, such as bronchial asthma?
T lymphocytes
Eosinophils
Plasma cells
Neutrophils
Macrophages
30s - Q8
What distinguishes chronic ulcer from an acute ulcer in the stomach or duodenum?
Bleeding
Lack of inflammation
Development of scar tissue with lymphocytes, macrophages, and plasma cells
Presence of only neutrophils
Absence of Helicobacter pylori
30s - Q9
Which factor primarily drives the formation of non-caseating granulomas in sarcoidosis?
Bacterial infection
Trauma
Unknown etiology
Viral infection
Gallstones
30s - Q10
What is the most common complication associated with chronic cholecystitis?
Intestinal obstruction
Liver cirrhosis
Peptic ulcer
Gallbladder fibrosis and shrinkage
Pulmonary embolism
30s - Q11
Which of the following conditions is an immune-mediated inflammatory disease commonly associated with chronic inflammation?
Hepatitis B
Myocardial infarction
Gallbladder stones
Rheumatoid arthritis
Influenza
30s - Q12
Which histological feature is characteristic of a caseating granuloma?
Central necrosis with an amorphous, eosinophilic appearance
Increased fibroblast activity
Absence of necrosis
Presence of only giant cells
Abundant collagen deposition
30s - Q13
Which condition is associated with asteroid bodies and Schaumann bodies within granulomas?
Sarcoidosis
Peptic ulcer disease
Tuberculosis
Rheumatoid arthritis
Crohn's disease
30s - Q14
What is the primary role of fibroblasts in chronic inflammation?
Synthesis of collagen for tissue repair and fibrosis
Phagocytosis of bacteria
Mediation of immune responses
Production of antibodies
Regulation of vascular tone
30s - Q15
In tuberculosis, what structure is formed by the combination of parenchymal and nodal involvement?
Cavitation
Miliary lesion
Caseous lesion
Langhans cell
Ghon complex
30s