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Dividing into Ratio
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The 4 elements of music Everyone loves music, but have you ever thought how many elements thereare in a piece of music? The answer is just four: melody, harmony, rhythm and dynamics. Let's take a closer look at them. Melody: This is the tune which we hear when we listen to a piece of music. The melody is made up of single tones, or pitches, played one after the other. When we talk about the tone or pitch of a sound, we mean how high or low it is. Harmony: There are a lot of different notes and chords. Harmony is how they sound when they are played at the same time. Even if you don’t know much about music, you'll know when a song isn’t in harmony because it will sound terrible! Rhythm: This means ‘musical time’. Rhythm helps to organise music by dividing it into small sections between each strong beat. There are a few different patterns, such as every two, three or four beats. We can play music at different speeds, too. We call the speed of music the tempo. Dynamics: These tell the musicians how to play a piece of music. Some parts are quiet, while others are loud. There aren't any rules for writing music, but musicians always think of these four elements when
Quadrants The abdominal wall is divided into 4 quadrants which are defined by 2 planes: 1. Transumbilical plane – horizontal plane through the umbilicus at the IVD between L3 – L4. 2. Median plane- vertical plane dividing the body into right and left halves.Abdominal Regions • The abdomen is divided into 9 regions so that organ location and pain can be described. • The regions are delineated by 4 planes: 1. Right and Left midclavicular planes 2. Subcostal plane (sometimes a transpyloric plane is used) 3. Transtubercular plane which passes through the L5 vertebral body.
Most of the functions of a eukaryotic cell are controlled by the nucleus, shown in Figure 4-12. The nucleus is filled with a jellylike liquid called the nucleoplasm, which holds the contents of the nucleus and is similar in function to a cell’s cytoplasm. The nucleus houses and protects the cell’s genetic information. The hereditary information that contains the instructions for the structure and function of the organism is coded in the organism’s DNA, which is contained in the nucleus. When a cell is not dividing, the DNA is in the form of a threadlike material called chromatin. When a cell is about to divide, the chromatin condenses to form chromosomes. Chromosomes are structures in the nucleus made of DNA and protein. The nucleus is the site where DNA is transcribed into ribonucleic acid (RNA). RNA moves through nuclear pores to the cytoplasm, where, depending on the type of RNA, it carries out its function. Nuclear Envelope The nucleus is surrounded by a double membrane called the nuclear envelope. The nuclear envelope is made up of two phos- pholipid bilayers. Covering the surface of the nuclear envelope are tiny, protein-lined holes, which are called nuclear pores. The nuclear pores provide passageways for RNA and other materials to enter and leave the nucleus. Nucleolus Most nuclei contain at least one denser area, called the nucleolus (noo-KLEE-uh-luhs). The nucleolus (plural, nucleoli) is the site where DNA is concentrated when it is in the process of making ribosomal RNA. Ribosomes (RIE-buh-SOHMZ) are organelles made of protein and RNA that direct protein synthesis in the cytoplasm. The nucleus of a cell is surrounded by a double membrane called the nuclear envelope. The nucleus stores the cell’s DNA. FIGURE 4-12 Nuclear envelope Nucleolus Nuclear pores DNA (chromatin) Copyright © by Holt, Rinehart and Winston. All rights reserved. 80 CHAPTER 4 MITOCHONDRIA Mitochondria (MIET-oh-KAHN-dree-uh) (singular, mitochondrion) are tiny organelles that transfer energy from organic molecules to adenosine triphosphate (ATP). ATP ultimately powers most of the cell’s chemical reactions. Highly active cells, such as muscle cells, can have hundreds of mitochondria. Cells that are not very active, such as fat-storage cells, have few mitochondria. Like a nucleus, a mitochondrion has an inner and an outer phos- pholipid membrane, as shown in Figure 4-13. The outer membrane separates the mitochondrion from the cytosol. The inner membrane has many folds, called cristae (KRIS-tee). Cristae contain proteins that carry out energy-harvesting chemical reactions. Mitochondrial DNA Mitochondria have their own DNA and can reproduce only by the division of preexisting mitochondria. Scientists think that mito- chondria originated from prokaryotic cells that were incorporated into ancient eukaryotic cells. This symbiotic relationship provided the prokaryotic invaders with a protected place to live and pro- vided the eukaryotic cell with an increased supply of ATP. RIBOSOMES Ribosomes are small, roughly spherical organelles that are respon- sible for building protein. Ribosomes do not have a membrane. They are made of protein and RNA molecules. Ribosome assembly begins in the nucleolus and is completed in the cytoplasm. One large and one small subunit come together to make a functioning ribosome, shown in Figure 4-14. Some ribosomes are free within the cytosol. Others are attached to the rough endoplasmic reticulum.
LAYERS (STRATA) OF THE EPIDERMIS Stratum Basale Single layer - cuboidal or columnar Mitotic stem cells Contain keratin filaments - as cells progress upwards, the amount and type of keratin filaments increase Basal cell carcinoma (rarely lethal) found here. Stratum Spinosum (usually the thickest) Polyhedral cells with central nucleus Synthesize keratin filaments which form bundles called tonofibrils; extend into spines Cells bound together by cytoplasmic spines (and desmosomes) - maintain cohesion and resist effects of abrasion Mitotic stem cells in deepest layer Squamous cell carcinoma develops here. Also, rarely lethal. ** stratum germinativum- sometimes reference for the basale layer and deepest layer of spinosum together actively dividing to provide new cells to replenish lost skin from normal shedding. stratum Granulosum -undergoes keratinization 3-5 layers of flattened cells Cells filled with coarse basophilic keratohyaline granules (filaggrin) Help pack keratin filaments together into larger structures Characteristic feature: Cells filled with lamellar granules Granules release contents (lipid) into intercellular space which envelop the cells Acts as a barrier against water loss from the skin Both types of granules create a seal (barrier) against foreign materials Cells begin process of apoptosis Transition area between deeper layers of metabolically active cells and dead cells of superficial layers