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General Anesthetics

Quiz by Abby Bennett

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23 questions
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  • Q1

    Which is NOT a GABA A positive modulator

    Inhaled Gas (Nitrous Oxide)

    IV - Ketamine

    IV - (Etomidate, Propofol)

    Volatile Liquids (Desflurane, Isoflurane, Sevoflurane)

    30s
  • Q2

    Inhaled Gas GABA A Receptor Positive Modulator

    Nitrous Oxide

    Ketamine

    Desflurane, Isoflurane, Sevoflurane

    Etomidate, Propofol

    30s
  • Q3

    Volatile Liquid GABA A Receptor Positive Modulator

    Desflurane, Isoflurane, Sevoflurane

    Ketamine

    Etomidate, Propofol

    Nitrous Oxide

    30s
  • Q4

    IV GABA A Receptor Positive Modulator

    Desflurane, Isoflurane, Sevoflurane

    Etomidate, Propofol

    Ketamine

    Nitrous Oxide

    30s
  • Q5

    GABA A Receptor MOA

    GABA Stim -> Cl- influx ->Reduced Neuronal Firing -> Hyperpolarization

    GABA Stim -> Hyperpolarization -> Cl- influx -> Reduced Neuronal Firing

    GABA Stim -> Reduced Neuronal Firing -> Hyperpolarization -> Cl- influx

    GABA Stim -> Cl- influx -> Hyperpolarization -> Reduced Neuronal Firing

    30s
  • Q6

    Volatile Liquid Toxicities

    All of the above

    Malignant Hyperthermia

    Induce PONV (post-operative nausea/vomiting)

    Do not use with ASTHMA/COPD (pungent airway irritant)

    30s
  • Q7

    Volatile Liquid Benefits

    Induce n/v 

    Induce bronchodilation (MOA Unclear)

    Tachycardia

    Induce bronchoconstriction (MOA Unclear)

    30s
  • Q8

    Most potent coronary vasodilator

    All of the above

    Sevoflurane

    Isoflurane

    Desflurane

    30s
  • Q9

    Which IV general anesthetic (GABA a + modulators) produces anti-emetic effects

    Etomidate

    none of the above

    Propofol

    Ketamine

    30s
  • Q10

    Triad relating to general anesthetics (goals)

    PNS Control, Unconsciousness, Immobility

    ANS Control, Unconsciousness, Immobility

    Sympathetic Nervous System Control, Unconsciousness, Immobility

    CNS Control, Unconsciousness, Immobility

    30s
  • Q11

    Which is correctly matched?

    Unconsciousness/Amnesia - Low dose

    May help control autonomic functions - High dose

    Contribute to Immobility - Moderate dose

    All of the above

    30s
  • Q12

    Opioids do all of the following (when combined with anesthetics) except:

    Cause analgesia and decrease risk of sympathetic "surgical stress" response

    Promote hypnosis and unconsciousness

    Promote sedation and unconsciousness

    Cause analgesia and reduce risk of nociception induced arousal

    30s
  • Q13

    Which is true about general anesthetics

    Potency correlates with hydrophobicity (low potency = low hydrophobicity)

    Potency correlates with hydrophobicity (high potency = low hydrophobicity)

    Potency correlates with hydrophobicity (low potency = high hydrophobicity)

    Potency correlates with hydrophobicity (high potency = high hydrophobicity)

    30s
  • Q14

    What is minimum alveolar concentration (MAC)

    concentration of IGA in lungs that results in anesthesia in 75% of patients

    concentration of IGA in lungs that results in anesthesia in 100% of patients

    concentration of IGA in lungs that results in anesthesia in 25% of patients

    concentration of IGA in lungs that results in anesthesia in 50% of patients

    30s
  • Q15

    Which of the following is true

    Solubility does not influence duration of onset

    Drugs that are more soluble take longer to take effect

    Drugs that are less soluble take longer to take effect

    Drugs that are more soluble take shorter to take effect

    30s

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