
General Anesthetics
Quiz by Abby Bennett
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- Q1
Which is NOT a GABA A positive modulator
Inhaled Gas (Nitrous Oxide)
IV - Ketamine
IV - (Etomidate, Propofol)
Volatile Liquids (Desflurane, Isoflurane, Sevoflurane)
30s - Q2
Inhaled Gas GABA A Receptor Positive Modulator
Nitrous Oxide
Ketamine
Desflurane, Isoflurane, Sevoflurane
Etomidate, Propofol
30s - Q3
Volatile Liquid GABA A Receptor Positive Modulator
Desflurane, Isoflurane, Sevoflurane
Ketamine
Etomidate, Propofol
Nitrous Oxide
30s - Q4
IV GABA A Receptor Positive Modulator
Desflurane, Isoflurane, Sevoflurane
Etomidate, Propofol
Ketamine
Nitrous Oxide
30s - Q5
GABA A Receptor MOA
GABA Stim -> Cl- influx ->Reduced Neuronal Firing -> Hyperpolarization
GABA Stim -> Hyperpolarization -> Cl- influx -> Reduced Neuronal Firing
GABA Stim -> Reduced Neuronal Firing -> Hyperpolarization -> Cl- influx
GABA Stim -> Cl- influx -> Hyperpolarization -> Reduced Neuronal Firing
30s - Q6
Volatile Liquid Toxicities
All of the above
Malignant Hyperthermia
Induce PONV (post-operative nausea/vomiting)
Do not use with ASTHMA/COPD (pungent airway irritant)
30s - Q7
Volatile Liquid Benefits
Induce n/v
Induce bronchodilation (MOA Unclear)
Tachycardia
Induce bronchoconstriction (MOA Unclear)
30s - Q8
Most potent coronary vasodilator
All of the above
Sevoflurane
Isoflurane
Desflurane
30s - Q9
Which IV general anesthetic (GABA a + modulators) produces anti-emetic effects
Etomidate
none of the above
Propofol
Ketamine
30s - Q10
Triad relating to general anesthetics (goals)
PNS Control, Unconsciousness, Immobility
ANS Control, Unconsciousness, Immobility
Sympathetic Nervous System Control, Unconsciousness, Immobility
CNS Control, Unconsciousness, Immobility
30s - Q11
Which is correctly matched?
Unconsciousness/Amnesia - Low dose
May help control autonomic functions - High dose
Contribute to Immobility - Moderate dose
All of the above
30s - Q12
Opioids do all of the following (when combined with anesthetics) except:
Cause analgesia and decrease risk of sympathetic "surgical stress" response
Promote hypnosis and unconsciousness
Promote sedation and unconsciousness
Cause analgesia and reduce risk of nociception induced arousal
30s - Q13
Which is true about general anesthetics
Potency correlates with hydrophobicity (low potency = low hydrophobicity)
Potency correlates with hydrophobicity (high potency = low hydrophobicity)
Potency correlates with hydrophobicity (low potency = high hydrophobicity)
Potency correlates with hydrophobicity (high potency = high hydrophobicity)
30s - Q14
What is minimum alveolar concentration (MAC)
concentration of IGA in lungs that results in anesthesia in 75% of patients
concentration of IGA in lungs that results in anesthesia in 100% of patients
concentration of IGA in lungs that results in anesthesia in 25% of patients
concentration of IGA in lungs that results in anesthesia in 50% of patients
30s - Q15
Which of the following is true
Solubility does not influence duration of onset
Drugs that are more soluble take longer to take effect
Drugs that are less soluble take longer to take effect
Drugs that are more soluble take shorter to take effect
30s