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11 questions
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  • Q1
    Which of the following drugs is likely to cause cholestasis?
    Chlorpromazine
    Paracetamol
    Amiodarone
    Aspirin
    30s
  • Q2
    A 29-year-old female is noted to have elevated bilirubin during a viral illness. Gilbert's syndrome is suspected. Which one of the following tests may confirm the diagnosis?
    Measure UGT1A1 activity
    Bromsulphthalein excretion test
    Faecal fat excretion
    Urine analysis
    30s
  • Q3
    Which one of the following drugs used in the management of diabetes mellitus is most likely to cause cholestasis?
    Gliclazide
    Pioglitazone
    Metformin
    30s
  • Q4
    Characteristic features of cholestatic jaundice include
    Normal serum alkaline phosphatase
    Dark green stool
    Conjugated hyperbilirubinemia
    30s
  • Q5
    Jaundice is clinically detectable when serum bilirubin is?
    A. 1.5mg/dL
    >5 mg/dl
    > 7 mg/dl
    > 3 mg/dl
    30s
  • Q6
    Which of the following is NOT associated with increased bilirubin in blood?
    Budd-Chiary syndrome
    Pulmonary alveolar proteinosis
    Dubin-Johnson syndrome
    30s
  • Q7
    The diagnosis of celiac disease is confirmed by?
    Barium meal follow
    Positive serology for celiac autoantibodies
    Chronic diarrhoea of foul smelling and bulky stools
    Histological evidence villous atrophy of duodenal biopsy specimen
    30s
  • Q8
    A 45-year-old patient with presented with intra-hepatic cholestatic jaundice is likely to have?
    Obstruction of bile flow through intra-or extrahepatic bile ducts.
    Elevated levels of un-conjugated bilirubinemia.
    Increased secretion of bile by hepatocytes.
    30s
  • Q9
    A 42 - year - old woman presents with a 1-year history of recurrent right upper quadrant pain and jaundice associated with pale stools and dark urine. The episode occurs after fatty meals, lasts for several hours, and is associated with nausea and vomiting.
    The dark urine is due to the presence of excess urobilinogen
    The most likely diagnosis is carcinoma of the head of the pancreas.
    The gallbladder is likely to be palpable
    The most appropriate first-line test is an abdominal ultrasound
    30s
  • Q10
    A 72 - year - old man known case of polycythemia rubra vera presents to the ED with a 2 - day history of abdominal pain. On examination, he is mildly jaundiced, and there are no signs of chronic liver disease, but he has a painful enlarged liver with moderate ascites. What is the most likely diagnosis?
    Budd– Chiari syndrome
    Acute alcoholic hepatitis
    Malignant infiltration of the liver
    Hepatitis A virus infection
    30s
  • Q11
    A 35- year- old man develops jaundice shortly after a bout of flu. This has happened to him several times in the past. Jaundice always resolves completely within a week, and he is well in between episodes. There is a similar history in his mother.
    Gall bladder stone
    Gilbert’s syndrome
    Paracetamol overdose
    Acute viral hepatitis
    30s

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