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Lecture 22

Quiz by Rund

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6 questions
Show answers
  • Q1

    The drug shown in the structure is a chiral drug, and its metabolism can be affected by the different stereoisomer, (T or F):

    Question Image
    true
    false
    True or False
    30s
  • Q2

    The metabolic reaction is:

    Question Image

     N-Demethylation

    Dehalogenation

    Oxidative Deamination

    N-Oxidation

    30s
  • Q3

    Morphine glucurondation reaction on OH group at position 6 gives a metabolite with:

    Question Image

    Both positions undergo glucuronidation at the same time

    Both positions do not undergo glucuronidation reaction 

    Different activity than OH at position 3

    Same activity as OH at position 3

    45s
  • Q4

    The metabolic reaction:

    Question Image

    Hydroxylation only

    Reduction

    N-dealkylation & Hydroxylation

    N-dealkylation only

    45s
  • Q5

    Drugs can generate metabolites that are:

    Less active than the parent

    More active than the parent

    Completely inactive 

    All

    45s
  • Q6

    Some drugs may possess metabolites with different activity, (T or F):

    true
    false
    True or False
    20s

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