Marker Analysis
Quiz by Kim Reid
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10 questions
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- Q1What is sporadic cancer?Cancer that is not due to an inherited gene mutationCancer that is due to an inherited gene mutationCancer that occurs in a family more than expected and is not inherited.30s
- Q2What is familial cancer?Cancer caused by an inherited genetic mutations.Cancer that occurs in families more often than would be expected by chance. They may also be a sign of shared environmental or lifestyle factors.Cancer that does not have an inherited link.30s
- Q3What is hereditary Cancer?Cancer that are caused by inherited gene mutationsCancer that occurs in families more often than would be expected by chance. They may also be a sign of shared environmental or lifestyle factors.Cancer that is not due to an inherited gene mutation30s
- Q4What does marker analysis tell us?The allele that is affectedThe length of the DNA sequenceThe DNA sequence30s
- Q5How are alleles determined using gel electrophoresis?By how long the gene sequence is.By the width of the gene sequenceBy the number repeats in the STR.30s
- Q6Why did the Dr believe Judy was a good candidate for marker analysis testing for breast cancer?Judy knew she had the BRCA 1 mutationThe Dr. had performed a biopsy.Her grandfather, mother and sister all developed breast cancer at an early age30s
- Q7During gel electrophoresis, which sample would move furthest down the gel?890 Bp length sample740 Bp length sample510 Bp length sample30s
- Q8The distance the DNA fragment migrated from the well divided by the distance from the well to the reference point is used to determine what value?AbBpRf30s
- Q9Based on our results in class, was Judy’s family occurrences of breast and ovarian cancers are sporadic, hereditary, or familial?Hereditaryfamilialsporadic30s
- Q10What did Judy and her two sisters all have in common that lead us to believe they have the BRCA mutation?All had breast cancerJennifer and Judy had breast cancer.All had the same allele present30s