
Myeloproliferative disorders
Quiz by Wayne Aguiar
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20 questions
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- Q1Myelodysplatic disorders are "best" characterized byincreases in one specific cell lineincrease in cellular elements (RBC, WBC and/or platelets)decrease in cellular elementsabnormal functioning cells30s
- Q2The primary defect in MPDmegakaryoblastmyelobasthematopoietic stem cellerythroblast30s
- Q3The feature(s) of MPD is/aretransformation to acute leukemiahypercellular marrow with fibrosisextramedullary hematopoiesisall of the answers are correct30s
- Q4The most common transformation of CML isAMLIMFALLET30s
- Q5What do ET, PV and CML all have in commontransform to AMLAre all MDS diseasestransform to ALLtransform to IMF30s
- Q6CML hastwo phasesfour phasesthree phasesone phase30s
- Q7What statements are true for CMLBCR-ABL gene fusiondefect is called philadelphia chromosomeall are trueChromosome 9 and 22 have a translocation30s
- Q8The terminal phase of CML is calledacute phasechronic phaseblast crisisaaccelerated phase30s
- Q9The advantage of using molecular techniques in CMLPinpoint detection of the translocation of Chromosome 9 and 22detect of PCdetect alternate cases of PD found in ALL or AMLdetect ABR BCL gene fusion in absence of PC30s
- Q10Philadelphia chromosome is also found inRare AML cases (2%)all of the aboveChildhood ALL (2-5%)Adult ALL (20%)30s
- Q11This is a picture consistent withCMLCLLAMLALL30s
- Q12The cells at the tip of the arrows are best identified aslymphsmyeloblastsBasophilseosinophils30s
- Q13Interpret the LAP stain, patient is on the right , control on the leftPatient has Leukamoid reaction, decreased LAPPatient has Leukamoid reaection with a increased LAPPatient has CML, increased LAPPatient has CML, decreased LAP30s
- Q14What is true of CML therapyhydroxyurea is usedall are truebone marrow transplant is usedtyrosine kinase inhibitors are used30s
- Q15Which of the following is a MPDEssential thrombocythemiaPolycythemia veraChronic Idiopathic Myelofibrosisall of them30s