Choose bad prognostic factors in acute lymphoblastic leukemia (ALL):

Children reach adult percentage of lymphocytes at the age of:

Methotrexate causes listed side effects EXCEPT:

A 4S stage neuroblastoma won’t be:

Choose correct recommendations for preventing acute tumor lysis syndrome:

Choose diseases with increased risk for developing Wilms tumor:

Chose mandatory tests in the diagnostic process of ALL :

Increased AFP level might be present in:

The most common localization for B-cell non-Hodgkin lymphoma is:

The most common congenital bleeding disorder is:

Choose INCORRECT sentence about Pneumocystis jiroveci (carinii) lung infections in children with ALL:

17 y.o. boy with 2 weeks history of pain located below the right knee. First symptoms started after soccer practise and pain increased with physical activity. On physical examination- no visible deformity, both legs have the same circufference, temperature and colour. No FH of thrombophilia. Choose recommended action:

Marker for rhabdomyosarcoma in children is:

Most common localization for osteosarcoma is/are:

Choose appropriate recommendation for a 10 y.o. boy with petechiae and bruses all over the body, without hepatosplenomegaly, without other abnormalities on PE. In history a viral infection of upper respiratory tract about 1 month ago. In CBC: WBC- 5000/mm3, Hgb- 12mg/dl (120 g/L), PLT- 10 000/mm3, peripheral blood smear: granulocytes- 54%, lymphocytes- 34%, monocytes- 6%, eosinophiles- 3%, basophiles- 3%.

Indication/indications for prophylactic iron supplementation is/are:

12 y.o. boy with 1 month history of painless enlargement of left testis (3 times the volume than the right one) as the only clinical presentation. Choose INAPPROPRIATE action:

A 3 years old girl with a history of prolonged jaudince in the neonatal period, requiring red blood cell transfusions is admitted to the hospital with fever, upper respiratory tract infection and pallor. In the family history- father after splenectomy and father’s brother after cholecystectomy and splenectomy. On physical examination yellowish tint of skin and mucosa is observed, spleen is palpable 3cm below left costal margin. The most probable diagnosis in this girl is:

A 5 years old boy with symmetrical enlargement of cervical lymph nodes, red throat, whitish plaques on tonsils, liver not enlarged, spleen palpable 2 cm under right costal margin. In CBC: WBC 13.70 x10'3/μL; RBC 3.72 x10'6/μL; HGB 10.7 g/dl (107g/L); HCT 31.1 %; MCV 83.6 fL; MCH 28.8 pg; MCHC 34.4 g/dl; PLT 171.0 x10'3/μL; in peripheral blood smear: myelocytes - 1 %; bands- 2 %; neutrophiles- 10 %; eosinophiles- 1 %; limphocytes- 82 %; monocytes- 4 %. In a diagnostic process we should take into account:

WBC- 9000/mm3, RBC- 3,4*10'6/mm3, Hgb- 12,2g/dl (102 g/L), PLT- 250 000/mm3 in 7 years old child indicate:

Leukocoria is characteristic of:

Opsomyoclonus ataxia is a paraneoplastic syndrome characteristic of:

Vena Cava Superior (VCS) syndrome is most commonly observed in patients diagnosed for:

Among Hodgkin lymphoma's B general symptoms are:

Macrocytic anemia is caused by:

Hemolytic anemia is not caused by:

The most common childhood malignancy in 1 year of life is/are:

Cardiotoxicity from cytoxic treatment may lead to congestive heart failure. Which one of the following drugs has a potential negative effect on cardiac function.

Severe type of hemophilia A is defined by:

In hemolytic anemia (choose incorrect feature):