According to the WHO classification, mature T-cell neoplasms are categorized based on all of the following EXCEPT:

Which chromosomal rearrangement is most characteristically associated with T-PLL and involves the TCL1 oncogene?

A unique immunophenotypic feature seen in a significant subset of T-PLL cases, which is rare in other post-thymic T-cell malignancies, is:

What is the approximate 5-year overall survival rate for T-PLL?

The pathogenesis of T-LGLL is strongly associated with constitutive activation of which signaling pathway?

Which of the following is the most frequent autoimmune association in T-LGLL?

The diagnostic criterion for T-LGLL includes an absolute peripheral blood LGL count greater than:

The immunophenotype of a typical T-LGLL is:

Which genetic mutation is most commonly associated with T-LGLL and is a marker of poorer prognosis?

A classic paraneoplastic syndrome frequently seen in the acute form of ATLL is:

The immunophenotype of ATLL is typically:

The diagnostic triad for Sézary Syndrome includes all of the following EXCEPT:

A key immunophenotypic aberration in Sézary cells is the loss of:

Which of the following flow cytometry findings is part of the ISCL diagnostic criteria for Sézary Syndrome?

Hepatosplenic T-cell lymphoma is characterized by a frequent association with:

The most common subtype of Peripheral T-Cell Lymphoma is:

The immunophenotype of Angioimmunoblastic T-cell Lymphoma (AITL) is defined by the expression of markers related to:

Which genetic mutation is highly characteristic of AITL, occurring in up to 70% of cases?

The defining immunophenotypic marker for all subtypes of Anaplastic Large Cell Lymphoma (ALCL) is:

ALK-positive ALCL is most commonly associated with which translocation?

Which variant of ALCL is most likely to present with a leukemic phase?

A 28-year-old man with a history of Crohn's disease on immunosuppressive therapy presents with fever, hepatosplenomegaly, and pancytopenia. A bone marrow biopsy shows an intrasinusoidal infiltrate of medium-sized lymphoid cells with irregular nuclei. Cytogenetics reveals isochromosome 7q. What is the most likely diagnosis?