It is a significant complication that results from the death of tumor cells and release of their content into the circulation, also defined as a severe metabolic abnormalities.

TLS may develop before cancer treatment even begins

TLS’ severe metabolic abnormalities includes hyperuricemia, hyperphosphatemia, hypocalecemia and hyperkalemia.

One metabolic abnormality or a combination of abnormalities can Occur and may lead to acute Renal failure and potentially life-threatening cardiac dysfunction.

 In giving dietary instruction to a patient diagnosed with TLS. Instruct to have atleast 1 banana per meal.

It is known as a drug of choice in treating hyperphosphatemia.

Hyperkalemia may cause ventricular arrhythmia.

Nursing assessement and intervention: what nursing diagnosis is the nurse’s priority?

Urine specific gravity must be kept at >1.010 and urine PH at 7-7.5 during treatment.

Patients diagnosed with T-cell ALL, Burkitt and other B-cell NHL are at risk to develop TLS.