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2 ovaries → follicles → oocyte Follicles: made of 1 oocyte + theca cells and granulosa cells Theca cells - make testosterone Granulosa cells - make estradiol Oocytes: fixed amount per lifetime (~400) Ovulation - when oocyte leaves the follicle Fertilization: Connects ovaries to uterus Open-system: fallopian tubes are open to peritoneal space → easy to get infection! NOTE: Endometriosis: when endometrial cells are found in places other than uterus Retrograde menstruation: shedding of endometrium → goes up to fallopian tube (instead of down to cervix → vagina) → enters peritoneal space → travels Endometrium: hormone-sensitive mucosal lining of the endometrium Non-pregnant menstrual cycle: bleeding = shedding of endometrium Pregnancy: endometrium doesn’t shed → implantation occurs here Myometrium: smooth muscle layer of uterus → contracts during period to shed endometrium → cramps Continuous with cervix Dilates during menses and during birth | Quizalize