A process which causes bleeding to stop

A coagulation test that measures the extrinsic system of coagulation and involves the addition of calcium chloride reagent and tissue factors

Assay that uses thrombin as a substrate to measure the time it takes to convert fibrinogen to fibrin

Naturally occuring inhibitor that neutralizes the action of thrombin, IXa, Xa, XIa, and XIIa, inhibiting coagulation; activity increases markedly when AT combines to Heparin

Are blood components that assist in the stoppage of bleeding by clumping and clotting damage blood vessels

Vitamin K dependent protein that inhibits clotting factors V and VIII when activated by thrombin-thrombomodulin complex

Vitamin K dependent protein that is required for activation of protein C

Is a Fibrous, non globular protein involved in the clotting of blood

Is a soluble protein in the plasma that is broken down to fibrin by enzyme thrombin to form blood clots

Hemostatic process involving enzymes activators, and inhibitors, resulting in plasmin digestion of fibrin and fibrinogen and subsequent clot dissolution and restoration of blood flow

Protein involved in wound healing and cell adhesion

Agent that prevents or delays blood coagulation

Naturally occurring or commercially manufactured anticoagulant, monitored by activated partial thromboplastin time or anti factor Xa heparin assay

Vitamin K antagonist compound that inhibits coagulation by acting against vitamin K dependent coagulation factors; monitored by prothrombin time test and INR

Autosomal recessive bleeding disorder associated with less than 10 mg/dl of fibrinogen

Heterozygous form of afrinogenemia associated with fibrinogen levels between 20 mg/dl and 100 mg/dl

Autosomal dominant fibrinogen disorder associated with abnormal fibrinogen molecule and abnormal clottable assay for qualitative fibrinogen

Autosomal dominant thrombotic disorder caused by mutation of Factor V; most common inherited cause of thrombosis

Blood clot that obstructs a blood vessel or a cavity of the heart

The formation of a blood clot inside a blood vessel that obstructs the blood flow throughout the circulatory system

Formation of a blood clot in the deep veins of the legs, arms, or pelvis

Condition triggered by many pathologic events in which the coagulation pathways are hyperstimulated by either excessive fibrin disposition or excess fibrinolysis; patients with DIC clot, bleed, or both

Heparin dependent hemostatic inhibitor enzyme that acts on thrombin

Immune mediated thrombocytopenia in a subset of patients on heparin therapy or exposed to heparin in catheters or IV flush

Sex linked recessive bleeding disorder caused by factor VIII deficiency

Sex linked recessive bleeding disorder caused by factor IX deficiency

Hydrolytic enzyme that digests fibrin and fibrinogen

Inactive precursor of plasmin synthesized in the liver; converted to plasmin when acted on by thrombin and tissue plasminogen activator

Converts plasminogen to plasmin, resulting in fibrin degradation

Second nost common inherited cause of thrombosis; caused by a single point mutation (G20210A)

Large multimeric glycoprotein with two important functons, mediating the adhesion of platelets to sites of vascular injury and binding and stabilizing factor VIII