Question 1

What is the main actor in primaryhemostasis?

Accepted Answer

Platelets

Answer

Blood vessels

Answer

Factor VIII

Answer

Fibrinogen

Question 2

What is the most common cause of bleedingtendency?

Accepted Answer

Thrombocytopenia

Answer

HemophiliaA

Answer

VonWillebrand Disease (VWD)

Answer

Thrombocytosis

Question 3

What is the trigger of the extrinsicpathway of coagulation process?

Accepted Answer

Tissue factor release

Answer

Activationof thrombin

Answer

Activation of factor IX

Answer

Platelet activation

Question 4

The most common cause of errors in coagulation tests is …

Accepted Answer

Pre-analytic factors

Answer

Export of results

Answer

Faulty technique

Answer

Improper device or machine

Question 5

If the patient has hematocrit above 60%,we need to ….

Accepted Answer

Increase the amount of blood added to sampling tube

Answer

Do not thing

Answer

Increase the amount of anticoagulant added to sampling tube

Answer

Reduce the amount of blood added to sampling tube

Question 6

The best protocol to obtain plasma for coagulation study is …

Accepted Answer

2000g x 15 min

Answer

1000g x 5 min

Answer

2000g x 10 min

Answer

3000g x 15 min

Question 7

How’d you store the sample sent forcoagulation study if you’re not going to do it immediately?

Accepted Answer

At RT for PT

Answer

At RT for aPTT and at 2-8 Celsius for PT

Answer

At 2-8 Celsius for PT

Answer

At2-8 Celsius for all studies

Question 8

After preparation, PT reagent is stable for…

Accepted Answer

5-7days in the fridge

Answer

Until expiry date

Answer

A.6hours at 37◦C

Answer

2hours in the fridge

Question 9

A sample sent for coagulation study would be rejected if …

Accepted Answer

Itis apparently hemolyzed

Answer

It came after 15 min. after sampling

Answer

Itis not in cold box

Answer

Itis lipemic

Question 10

PT is important to evaluate …

Accepted Answer

All are true

Answer

Factor VII activity

Answer

Treatment with oral anticoagulant

Answer

Common pathway activity

Question 11

PTT is important to evaluate

Accepted Answer

Intrinsic pathway factors

Answer

Platelet function

Answer

Oral anti-coagulant activity

Answer

Primary hemostasis

Question 12

INR

Accepted Answer

Used to achieve inter-laboratory harmony in PT results

Answer

International normal range

Answer

State a normal range for PT

Answer

Used to monitor heparin therapy

Question 13

Fibrinogen assay by Clauss method…

Accepted Answer

Can detect hypo- and dys-fibrinogenemia

Answer

Immunogenic assay of fibrinogen level

Answer

none is ture

Answer

Is not required if we do thrombin time (TT)

Question 14

First-line hemostatic investigation include the following except…

Accepted Answer

Mixing study

Answer

PT

Answer

Platelet count

Answer

PTT

Question 15

Normal first line investigation with clinical bleeding may suggest…

Accepted Answer

all are true

Answer

Platelet function disorder.

Answer

Factor XIII deficiency

Answer

Mild VWD.

Question 16

Prolonged both PT and PTT with normal fibrinogen and platelet count may suggest…

Accepted Answer

Oral anticoagulant.

Answer

Hemophilia B

Answer

Factor VII deficiency.

Answer

all are true.

Question 17

Prolonged aPTT with normal other first-line investigation may suggest …

Accepted Answer

VWD

Answer

Factor X deficiency

Answer

Hypofibrinogenemia

Answer

Normal hemostasis

Question 18

Mixing study (correction study) means …

Accepted Answer

Mix patient’s plasma with normal plasma and repeat the clotting time.

Answer

Repeat the clotting times

Answer

none is true

Answer

Run the tests in replicates

Question 19

Upon mixing study the PT is not corrected. This would suggest…

Accepted Answer

Coagulation inhibitor

Answer

Hypofibrinogenemia

Answer

all are true

Answer

Factor VII deficiency

Question 20

Corrected PTT after mixing with normalplasma …

Accepted Answer

Intrinsic factor deficiency

Answer

Fibrinolytic abnormality

Answer

extrinsic factor deficiency

Answer

factor inhibitor

Question 21

Why is it important to use factor-deficient plasma in factor assays?

Accepted Answer

To isolate the specific factor being tested

Answer

To increase the sensitivity of the test

Answer

Toensure accurate platelet counts

Answer

To calibrate the equipment

Question 22

What is thrombophilia?

Accepted Answer

A hypercoagulable state leading to increased risk of blood clots

Answer

A bleeding disorder

Answer

A deficiency in clotting factors

Answer

A condition where the blood has a decreased tendency to clot

Question 23

Which of the following is an acquired risk factor for thrombosis?

Accepted Answer

Prolonged immobility

Answer

Antithrombin deficiency

Answer

Factor V Leiden mutation

Answer

Protein C deficiency

Question 24

Why is it important to test for thrombophilia?

Accepted Answer

To identify underlying causes of thromboembolism and decide on appropriate management.

Answer

To diagnose vitamin K deficiency

Answer

To ensure all patients receive anticoagulation therapy

Answer

It always affects the therapeutic strategy

Question 25

Which test should NOT be performed while a patient is on anticoagulant therapy?

Accepted Answer

Antithrombin functional activity

Answer

Genetic test for Factor V Leiden

Answer

Prothrombin Time (PT)

Answer

Activated Partial Thromboplastin Time (aPTT)

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