Question 1

Which of the following assays is primarily used to assess platelet function?

Accepted Answer

Platelet function assay (PFA)

Answer

Complete blood count (CBC)

Answer

Activated partial thromboplastin time (aPTT)

Answer

Prothrombin time (PT)

Question 2

What substance is commonly used to activate platelets in a platelet function assay?

Accepted Answer

Adenosine diphosphate (ADP)

Answer

Thrombin

Answer

Calcium chloride

Answer

Prothrombin

Question 3

In a platelet function assay, what does a prolonged closure time typically indicate?

Accepted Answer

Platelet dysfunction

Answer

Increased platelet count

Answer

Autonomous clotting factor

Answer

Normal platelet function

Question 4

Which condition is most likely to show abnormal results in a platelet function assay?

Accepted Answer

Aspirin use

Answer

Iron deficiency anemia

Answer

Vitamin K deficiency

Answer

Hemophilia

Question 5

Which of the following is a common method used to perform a platelet function assay?

Accepted Answer

Luminometric aggregometry

Answer

High-performance liquid chromatography (HPLC)

Answer

Electrophoresis

Answer

Flow cytometry

Question 6

What is the primary purpose of a platelet function assay?

Accepted Answer

To evaluate platelet aggregation ability

Answer

To assess coagulation factor deficiencies

Answer

To analyze red blood cell morphology

Answer

To measure hemoglobin levels

Question 7

Which platelet function assay evaluates the function of platelets by measuring the time taken for a blood sample to occlude a specific aperture?

Accepted Answer

Platelet function analyzer (PFA-100)

Answer

Thromboelastography

Answer

Bleeding time test

Answer

Clotting time test

Question 8

Which platelet function assay is considered to provide a direct measurement of platelet aggregation in response to various agonists?

Accepted Answer

Whole blood aggregometry

Answer

Complete blood count (CBC)

Answer

Prothrombin time (PT)

Answer

Activated partial thromboplastin time (aPTT)

Question 9

Which laboratory test can specifically differentiate between platelet function disorders and other bleeding disorders?

Accepted Answer

Platelet function assay (PFA)

Answer

Activated partial thromboplastin time (aPTT)

Answer

Blood smear examination

Answer

Prothrombin time (PT)

Question 10

What is the role of collagen in a platelet function assay?

Accepted Answer

To stimulate platelet adhesion and activation

Answer

To measure prothrombin levels

Answer

To inhibit platelet function

Answer

To determine the presence of leukocytes

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