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Protein Synthesis and DNA
Quiz by Julie Brown
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SB2. Obtain, evaluate, and communicate information to analyze how genetic information is expressed in cells. a. Construct an explanation of how the structures of DNA and RNA lead to the expression of information within the cell via the processes of replication, transcription, and translation. Learning Targets _______Identify the structural components of DNA and RNA Success Criteria _______Can accurately identify the key structural components of DNA (deoxyribose sugar, phosphate group, nitrogenous bases: adenine, thymine, cytosine, guanine). _______Can identify the key structural components of RNA (ribose sugar, phosphate group, nitrogenous bases: adenine, uracil, cytosine, guanine). _______Can describe the differences in the sugar backbone of DNA and RNA (deoxyribose vs. ribose). _______Can identify the double-stranded structure of DNA and the single-stranded structure of RNA. _______Identify the parts of protein synthesis and the location of each process Success Criteria _______Can identify and describe the two main processes of protein synthesis: transcription and translation. _______Can correctly explain that transcription occurs in the nucleus where DNA is transcribed into mRNA. _______Can explain that translation occurs in the cytoplasm at ribosomes where mRNA is translated into amino acid sequences to form proteins. _______Compare and Contrast DNA to RNA Success Criteria _______Can clearly identify similarities between DNA and RNA, such as both being nucleic acids and containing nucleotide structures. _______Can explain differences in DNA and RNA, including sugar types (deoxyribose vs. ribose), strand number (double-stranded DNA vs. single-stranded RNA), and nitrogenous base usage (thymine in DNA vs. uracil in RNA). _______Can describe the function of DNA as genetic storage and the function of RNA in protein synthesis (mRNA, tRNA, rRNA). _______Analyze the reasoning for enzymes usage in both DNA replication and protein synthesis. Success Criteria _______Can identify key enzymes involved in DNA replication (e.g., helicase, DNA polymerase, ligase) and explain their functions (e.g., helicase-unwinding DNA, DNA polymerase-synthesizing new DNA strands, ligase-sealing nicks in the DNA backbone). _______Can identify enzymes involved in protein synthesis (e.g., RNA polymerase) and explain their role in transcribing DNA into mRNA. _______Can analyze why enzymes are essential for speeding up chemical reactionsâŚ(ensuring accuracy, and catalyzing steps in replication and protein synthesis) _______Can provide specific examples of how enzyme malfunction can impact genetic replication or protein synthesis. _______Perform the steps of DNA replication and protein synthesis in order to demonstrate their understanding of how the structure of DNA supports the genetic expression in successive generations. Success Criteria _______Can demonstrate a step-by-step understanding of DNA replication, including unwinding, complementary base pairing, and proofreading. _______Can demonstrate the steps of transcription (formation of mRNA from DNA) and translation (conversion of mRNA into a polypeptide). _______Can show how DNA's structure (double helix, base pairing) ensures accurate replication for passing genetic information to offspring. _______Can illustrate how changes in DNA sequence can lead to changes in protein structure and function, thus affecting traits in successive generations.
Animal Cells Animal cells contain many organelles, which are subunits within the cell that perform specialized functions. The organelles may be membrane-bound (enclosed within a lipid bilayer) or non-membrane bound (free in the cytoplasm). Here is a list of animal cell components and organelles and their functions: ⢠Cell Membrane: The cell membrane or plasma membrane is a selectively permeable lipid bilayer that encloses the contents of the cell and regulates the transport of materials into and out of it. ⢠Cytoplasm: The cytoplasm is the jelly-like fluid that gives a cell is shape and contains the molecules the cell needs for its processes. ⢠Cytoskeleton: The cytoskeleton is a network of protein fibers that provides structural support, maintains cell shape, and enables cell movement. It is composed of three main types of protein filaments: microfilaments, intermediate filaments, and microtubules. ⢠Nucleus: The nucleus is the control center of the cell, containing DNA and regulating gene expression. It is surrounded by a double-layered nuclear envelope or nuclear membrane that has nuclear pores that allow the exchange of materials between the nucleus and the cytoplasm. Nucleolus: Located within the nucleus, the nucleolus is the site of pre-ribosome production. ⢠Mitochondria: Often referred to as the âpowerhouseâ of the cell, mitochondria are responsible for generating energy in the form of adenosine triphosphate (ATP) through cellular respiration. ⢠Endoplasmic Reticulum (ER): The ER is a network of membrane-bound tubes and sacs involved in the synthesis, folding, and transport of proteins and lipids. There are two types of ER: the rough ER, which is studded with ribosomes and involved in protein synthesis, and the smooth ER, which is responsible for lipid synthesis and detoxification. ⢠Ribosomes: These small structures, composed of RNA and proteins, are the sites of protein synthesis within the cell. They can be found either free-floating in the cytoplasm or attached to the rough ER. ⢠Golgi Apparatus: The Golgi apparatus is responsible for modifying, sorting, and packaging proteins and lipids for transport to their final destinations within or outside the cell. ⢠Lysosomes: Lysosomes are membrane-bound organelles containing enzymes that break down waste materials and cellular debris, playing a crucial role in the recycling of cellular components. ⢠Peroxisomes: These small organelles contain enzymes that neutralize toxic substances and break down fatty acids, contributing to cellular detoxification and energy production. ⢠Centrosome: The centrosome is an organelle found in animal cells but not plant cells. It is a small organelle near the nucleus with radiating tubules. The centrosome produces and organizes microtubules and regulates cell division so that the cell contents equally divide between daughter cells.
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