DDS Lab: Semi-Solid Dosage Forms

Topical applications can be designed for only for local effects or systemic absorption.

Semisolid preparations intended for external application to the skin or mucous membranes.

ointments are prepared either by incorporation and fusion. Incorporation is the use of heat while mixing the components. 

It is the determination of the net weight or volume of the contents of filled containers to ensure proper contents compared with the labeled amount.

Storage of semi solid preparations

Semisolid preparations containing one or more medicinal agents dissolved or dispersed in either a water-in-oil (W/O) emulsion or an oil-inwater (O/W) emulsion or in another type of water-washable base.

Many patients and physicians prefer creams to ointments because they are easier to spread and remove. 

Gels are solid systems consisting of dispersions of small or large molecules in an aqueous liquid vehicle rendered jellylike by the addition of a gelling agent.

Gels are stored in tight containers.

Single-phase gels are gels in which the macromolecules are uniformly distributed throughout a liquid with no apparent boundaries between the dispersed macromolecules and the liquid.

They generally contain a larger proportion of solid material (such as 25%) than ointments and therefore are stiffer.

Because of the stiffness of pastes, they remain in place after application and are effectively employed to absorb serous secretions. Because of their stiffness and impenetrability, pastes are suited for application to hairy parts of the body.

Solid or semisolid adhesive masses spread on a backing of paper, fabric, moleskin, or plastic.

In packaging a semi solid preparation, opaque jars is used for light sensitive products. They are colored porcelain white, dark green, or amber.

Plastic masses containing gelatin (15%), glycerin (40%), water (35%), and an added medicinal substance (10%), such as zinc oxide. 

Remember the percent composition ng semi solid na ito. Never to nawala sa board exam. Congrats in finishing the games.