Question 1

What is the primary mechanism by which superantigens activate T-cells?

Accepted Answer

By binding directly to the T-cell receptor and MHC class II molecules

Answer

By inducing apoptosis in T-cells

Answer

By binding solely to MHC class I molecules

Answer

By increasing antibody production

Question 2

Which of the following diseases is commonly associated with superantigen activity?

Accepted Answer

Toxic Shock Syndrome

Answer

Rheumatoid Arthritis

Answer

Multiple Sclerosis

Answer

HIV/AIDS

Question 3

What type of immune response is primarily mediated by superantigens?

Accepted Answer

A hyperactive T-cell response

Answer

A cytotoxic T-cell response

Answer

A specific antibody response

Answer

A suppressed immune response

Question 4

Which of the following is a characteristic feature of superantigens?

Accepted Answer

They activate a large proportion of T-cells non-specifically

Answer

They require specific antigen-peptide binding

Answer

They only activate B-cells

Answer

They are processed by antigen-presenting cells

Question 5

What is a potential consequence of superantigen exposure in the human body?

Accepted Answer

Cytokine storm

Answer

Localized inflammation

Answer

Decreased immune response

Answer

Antibody deficiency

Question 6

Which bacteria is known to produce superantigens associated with food poisoning?

Accepted Answer

Staphylococcus aureus

Answer

Listeria monocytogenes

Answer

Salmonella enterica

Answer

Escherichia coli

Question 7

Which of the following statements about superantigens is TRUE?

Accepted Answer

They bypass normal antigen processing and presentation mechanisms

Answer

They require specific recognition of peptide antigens

Answer

They can only be produced by viruses

Answer

They activate only a small subset of T-cells

Question 8

What is the role of superantigens in autoimmune diseases?

Accepted Answer

They may trigger inappropriate immune responses against self-antigens

Answer

They solely act against viral infections

Answer

They enhance vaccine efficacy

Answer

They prevent any immune response

Question 9

In which part of the immune system do superantigens primarily exert their effects?

Accepted Answer

On T-cells

Answer

In the bone marrow

Answer

On B-cells

Answer

In the bloodstream

Question 10

How do superantigens affect the production of cytokines in response to infection?

Accepted Answer

They can lead to an overproduction of pro-inflammatory cytokines

Answer

They induce only anti-inflammatory cytokines

Answer

They completely stop cytokine production

Answer

They double the production of antibodies

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