A 76-year-old man undergoes radical resection of the floor of the mouth and reconstruction with a free tissue transfer. Which of the following is an absolute contra-indication for the use of the microvascular arterial anastomotic coupler? 

A 39-year-old woman successfully undergoes immediate bilateral breast reconstruction with coverage with free deep inferior epigastric artery perforator free flaps. Postoperative flap monitoring is planned. Vascular compromise is most likely to occur during which of the following time periods postoperatively? 

A 55-year-old man with a history of squamous cell carcinoma undergoes glossectomy and reconstruction with a free radial forearm flap. Intraoperatively, the patient experiences hypotension, and norepinephrine is administered. Which of the following is the most likely effect of this treatment on the outcome of the free flap? 

A 45-year-old woman with rectal cancer is scheduled to undergo abdominoperineal resection and posterior vaginectomy following neoadjuvant chemotherapy and radiation therapy. Which of the following is the most appropriate method of reconstruction of the posterior vaginal defect?

A 58-year-old man comes to the office with recurrent rectal cancer four years after undergoing low anterior resection with adjuvant radiotherapy. Open abdominoperineal resection is planned. Which of the following closure methods will most reliably reduce the incidence of perineal wound complications?