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CKD: MBD

Quiz by Heather Powell

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14 questions
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  • Q1
    Which of the following is NOT associated with calcium and phosphorus homeostasis in CKD:MBD?
    FGF-23
    Vitamin D
    PTH
    Insulin
    30s
  • Q2
    Nephron loss leads to ____________ renal excretion of phosphate causing ________ serum phosphate concentrations.
    Decreased, Decreased
    Decreased, Increased
    Increased, Increased
    Increased, Decreased
    30s
  • Q3
    Hyperphosphatemia will cause _______ production of PTH
    increased
    decreased
    30s
  • Q4
    Hypocalcemia will cause _______ production of PTH
    decreased
    increased
    30s
  • Q5
    PTH will _________ serum calcium by ______________ bone resorption
    decrease, increase
    increase, decrease
    decrease, decrease
    increase, increase
    30s
  • Q6
    PTH works in all of the following ways except:
    increased active vitamin d production
    increased bone resorption
    increased renal calcium reabsorption
    decreased renal phosphate reabsorption
    30s
  • Q7
    Increased FGF-23 production will cause __________ active vitamin D function
    increased
    decreased
    30s
  • Q8
    First line treatment in hyperphosphatemia secondary to CKD: MBD?
    dietary phosphate restrictions
    IV calcium
    non-elemental phosphate binders
    calcium-containing phosphate binders
    30s
  • Q9
    Which of the following is NOT an appropriate strategy to treat hypercalcemia of CKD:MBD?
    Initiate calcitriol
    Replace calcium-containing phosphate binders with non-elemental phosphate binders
    Reduce PO calcium intake
    Discontinue ergocalciferol
    30s
  • Q10
    Which of the following is NOT an appropriate treatment strategy for hypocalcemia associated with CKD:MBD?
    discontinue cinacalcet
    use calcium-containing phosphate binders
    IV calcium if corrected ca < 8.5 mg/dL, symptomatic, and PTH above target
    Discontinue vitamin D supplementation
    30s
  • Q11
    True or False: Active vitamin D sterols should be reserved for patient with eGFR less than or equal to 29 ml/min/1.73m2, vitamin d < 30 ng/mL, and PTH > 300 g/dL.
    False
    True
    30s
  • Q12
    True or False: In patients with vitamin D levels between 15-30 ng/mL, replace with ergocalciferol 50000 units per week x 12 weeks, then monthly.
    False
    True
    30s
  • Q13
    At what calcium level should vitamin D therapy be discontinued?
    >11
    >10
    >11.5
    >10.5
    30s
  • Q14
    Cinacalcet produces a very potent ____________ in PTH
    decrease
    increase
    30s

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